Immune complexes composed of IgG 1-3 antibodies and food allergies trigger type III food allergies. In this case, allergens are marked as foreign by IgG 1-3 antibodies. The same process also occurs with bacteria, viruses, and other harmful substances. Antibody-immune complexes migrate through the immune complex via lymph and blood and lodge in the tissue.
To remove the resulting immune complex, neutrophil leukocytes release aggressive proteolytic enzymes that trigger chronic inflammatory processes.
This reaction only ends after the affected food is discontinued. The symptoms caused by type III allergies only appear some time after the food is consumed and only gradually subside after some time.
Specialized laboratories can detect IgG 1-3 subclass antibodies and thus the presence of type III allergies in the blood.
IgG-mediated type III allergies can cause a wide range of symptoms. The most common are inflammatory skin diseases such as acne, eczema, and psoriasis, as well as inflammatory bowel and digestive disorders. Type III allergies can also cause obesity, high blood pressure, arthritis, and other rheumatic diseases.
Although IgC antibodies are often surprisingly effective, they are not a panacea, as food intolerances and allergies represent a broad and complex clinical picture. These diseases can also be triggered by other pathologies.
This type of immune reaction can have various causes, is still little researched and, like the importance of IgC antibodies in inflammatory diseases, remains the subject of controversial discussions.
Type III allergy often co-occurs with other underlying diseases and presents with symptoms similar to those of other pathologies. Therefore, a thorough medical history and differential diagnostic knowledge are essential.
Possible triggers are:
- Primary lactose or fructose intolerance
- A reduced intestinal flora
- A strong yeast colonization in the intestine
- An enzyme deficiency
- Genetic causes
- Increased permeability of the intestinal mucosa
- Environmental toxins
- Severe malnutrition
- Premature contact with foreign proteins
In recent years, the very complex analysis of the effectiveness of IgG antibodies to food has been the focus of fierce criticism from the press and medical specialists.
I believe that a lack of information, too brief anamnesis, misleading and inferior laboratory analyses, and poor patient education have led to many misunderstandings. Type III allergy, which is triggered by IgG 1-3, is often confused with the presence of IgG 4. IgG 4 is an antagonist of IgE immunoglobulins and is actually unsuitable for Diagnostics a type III food intolerance.
In addition, most medical research is funded by the pharmaceutical industry, which has no interest in comprehensive nutritional analysis – a relatively new development in laboratory medicine.
A recent double-blind crossover study conducted at the University of Zurich showed that the symptoms of Crohn's disease patients – particularly stool frequency, abdominal discomfort and general well-being – can be significantly reduced by an elimination diet based on ImmuPro 300.
This result supports the theory that the consumption of foods that putatively produce specific IgG antibodies triggers chronic inflammation and is therefore clinically relevant for chronic inflammatory diseases such as Crohn's disease.
In my extensive clinical experience with chronic inflammatory skin diseases, gastrointestinal diseases, obesity, and rheumatic diseases, I have observed how countless patients with a proven IgG antibody reaction to food were quickly cured of chronic pain or experienced a significant improvement in their subjective well-being after consistently adhering to the elimination diet.
